Integrity

Essential knowledge to empower your drug discovery and development

Highlights

  • Drug R&D information
  • Integrated database
  • Export & reporting tools
  • Updated daily

Intended for

  • Biologist
  • Chemist
  • Pharmacologist

Description

Thomson Reuters Integrity℠ provides researchers with reliable, detailed information, from the perspective of a scientist, across multiple disciplines to support successful drug research and development.

Updated daily, its expertly refined drug information is integrated in a single, flexible resource that can help to drive innovation and support earlier decision-making.

Visit the Life Sciences Research site for more information on Disease Understanding.

Features

  • Drugs & Biologics: Essential chemical and pharmacological information, and the development status of bioactive compounds in the drug pipeline.
  • Experimental Pharmacology: Data from experimental studies that delineate drug/receptor and enzyme/target cell interactions.
  • Experimental Models: Animal models data used in drug development.
  • Pharmacokinetics/Metabolism: Data from experimental and clinical studies that delineate the absorption, distribution, metabolism and excretion (ADME) profile of a drug.
  • Organic Synthesis: Routes of synthesis (schemes, intermediates, reagents, end products) for drugs currently on the market or in development.
  • Disease Briefings: Dynamic executive summaries on the current status of and future trends in drug therapy.
  • Genomics: Genes and diseases information and their relationships into the underlying biological mechanisms.
  • Targets & Pathways: Precedented targets data and their role in pathological pathways.
  • Clinical Studies: Information on clinical trials of drugs currently under study or in use in humans.

Benefits

  • Make smart, fast decisions that empower your drug R&D and reduce your time to market.
  • Rapidly access recent, relevant and refined scientific information
  • Make faster and better decisions with advanced knowledge management tools
  • Lower risk and prioritize your projects using information integrated from multiple fields of drug R&D
  • Stay at the cutting edge of drug research and development with daily updates

Display Settings

The application is best viewed at a monitor resolution of 1024 by 768 pixels or higher, and at 256 colors or more (High Color or True Color recommended).

Browser Requirements

Microsoft® Internet Explorer version 6.0 or higher, or alternatively Mozilla Firefox® 3.6 or higher, within a Windows XP or higher operating environment. Internet Options: Exported results/reports are downloaded into a separate browser window. You must therefore ensure you temporarily disable/turn off any pop-up blockers on your computer, since the content will not export correctly when a pop-up blocker is active.

Javascript

The application uses JavaScript for defining menus and navigation, opening new windows and for the processing of requests. You must therefore enable the JavaScript option within your web browser to use the application successfully.

Cookies

In order to utilize all of the features available in the application, we recommend updating your Internet settings to enable or allow cookies for this website.

Adobe Reader

The application provides some exports in PDF format, to enable easy viewing and printing. You must therefore ensure that Adobe Reader is installed on your machine to export successfully. Adobe Reader is available for download free of charge, from the Adobe website.

Adobe Flash

Certain features are based on Adobe Flash technology, which is available for download free of charge from the Adobe website.

Case Study

Integrity Case Study

Drug discovery process made easier with the relevant search results from Thomson Reuters Integrity

Case Study

Integrity Case Study

Drug repurposing for rare disease treatments leads to reduced risk, cost, and development time.

Case Study

Integrity Case Study

How experimental models in Thomson Reuters Integrity can accelerate and enhance a pharmacologist's workflow

Case Study

BioMarker Case Study

Thomson Reuters Biomarker Solutions: Hepatitis C Treatment Biomarkers and special considerations in patients with Asthma

White Paper

BioMarker White Paper

White paper establishing the standards in biomarker research.

White Paper

BioMarker White Paper

Biomarkers: An indispensible addition to the drug development toolkit

Case Study

Integrity Case Study

Thomson Reuters Integrity identifies new business opportunities for Custom Synthesis Organizations

Case Study

Integrity Case Study

Thomson Reuters Integrity Supports new business opportunities for Discovery Alliance Organizations

Report

Integrity Report

The Changing Role of Chemistry in Drug Discovery

Case Study

BioMarker Case Study

The Combination of MetaCore and Thomson Reuters Integrity enables faster drug discovery

Case Study

BioMarker Case Study

Searching for contextual information surrounding the complete landscape of an individual Biomarker

Download Fact Sheet

Fact Sheets