Recorded Event: Current Interest in Bayesian Statistics

Listen to Kathy Foley, PhD, and David Smith, PhD, discuss current interest in Bayesian statistics and how it can be applied in outcomes research. The seminar covers:

  • Current interest in Bayesian statistics
  • What the technique is and how it was developed
  • How this statistical method follows our natural thought process
  • How this method is different from frequentist statistics
  • The advantage and disadvantages of using Bayesian statistics

Presentation slides

Recorded Event: Optimizing Observational Data for Comparative Effectiveness Research

Observational studies are a timely, cost-effective method for comparing the real-world effectiveness of various treatment options. However, the validity of these studies can be compromised by confounding factors and selection bias unless adequately addressed by the research design and during the analysis. In this seminar, Tami Mark, PhD, discusses:

  • Primary methods by which confounding can be addressed in observational research
  • Ways in which administrative data can be enhanced through links to supplemental sources such as surveys, absenteeism information, laboratory results, registries, and other clinical data

Presentation slides

Recorded Event: Using Mosaic Plots to Display Data

DATA VISUALIZATION WEB SEMINAR

Simple graphical summaries exist to enhance the inferential process of data analysis for most continuous-valued measurements.  Fewer types of techniques exist to summarize discrete data in a graphical format. 
Paul Juneau, senior statistician, introduces the idea of a mosaic plot and illustrates its use as a means of summarizing data in a contingency table. 

The seminar  takes  participants through:

  • Graphical representations of information: A brief philosophical excursion
  • Examples of typical graphical representations of data in contingency tables
  • An introduction of the mosaic plot visualization technique
  • An application example
  • Available software

Presentation slides

Recorded Event: Selecting PRO Statistical Endpoints


When designing the PRO component of your clinical trial, you want to select PRO statistical endpoints that demonstrate a clear treatment benefit for your product and match your PRO concept. 

Dennis D. Gagnon, MA, MABE, Sr. Director of Strategic Consulting, will discuss a five-point checklist you can use to ensure you are choosing the most appropriate statistical endpoint for PROs included in your clinical trials.

The seminar will use illustrative examples to highlight:

  • The relationship between the major study hypotheses and the PRO hypothesis
  • The right questions to ask in choosing the PRO statistical endpoint so as to adequately measure the expected PRO effects of the study drug
  • The criteria to consider in selecting the right PRO statistical endpoints - a five-point check list

Presentaion slides

No podcasts available at this time.

 

Video: The Value of Observational Data in Comparative Effectiveness Research

William D. Marder, PhD, discusses the importance of including observational data in comparative effectiveness research.

Video: Taking Comparative Effectiveness Research Out of the Clinic

Ron Z. Goetzel, PhD, talks about the importance of prevention and lifestyle interventions within the context of comparative effectiveness research.

Video: CER: At What Price?

William D. Marder, PhD, discusses the economics of comparative effectiveness research (CER).