The white papers illustrate how healthcare researchers use Thomson Reuters real-world data in published studies and research projects.

Choosing Pro Statistical Endpoints To Maximize Successful Outcomes

This white paper focuses on the probability of finding positive clinical trial outcomes that are improved when focus is put on understanding the relationships between research hypotheses, study design, and patient-reported outcomes (PRO) statistical endpoints. A five-point checklist is introduced to ensue you are choosing the most appropriate statistical endpoint for PROs included in your clinical trials.

Using Marketscan Data For Health Economic Modeling Studies

This white paper focuses on health economic models that are crucial for establishing the economic value and budgetary impact of pharmaceuticals and healthcare technologies.  Models built with claims data enable realistic evaluations of healthcare technologies, pinpoint specific settings most favorable for particular products, identify the most promising opportunities for novel therapies in current treatment paradigms, and help position products in the most favorable markets.

Health Research Data for the Real World: The MarketScan Databases (The MarketScan white paper)

This white paper describes the features and research uses of the databases in the Thomson Reuters MarketScan family. Specifically, the paper examines the unique features of individual databases, shows how these databases are constructed, describes their uses and data elements, and highlights examples of published studies based on MarketScan data.

The Value of Understanding Health and Productivity Costs: The MarketScan Health and Productivity Management Database. (The Health & Productivity white paper)

This white paper describes the impact of illness on employee productivity and the value of a health and productivity focus for the pharmaceutical industry. In addition, it explores why employers are increasingly investing in health and productivity management, and highlights the Thomson Reuters MarketScan Health and Productivity Management Database as a substantial data resource for conducting studies on the direct and indirect cost of illness and disease. Examples of published research based on MarketScan Health and Productivity Management data are included.

MarketScan in Action: Epidemiological Studies (The Epi white paper)

This white paper summarizes several epidemiology studies based on MarketScan data.
Topics include:

• Drug treatment patterns, adherence, and persistence
• Treatment outcomes and adverse events
• Vaccination and disease prevention
• Disease symptoms and severity

White paper: Medicare Part D Improves the Economic Well-Being of Low Income Seniors

This white paper provides an overview of research conducted to determine how enrollment in Medicare Part D impacts the economic well-being of low income seniors. This research was sponsored by Pharmaceutical Research and Manufacturers of America (PhRMA) and conducted by Thomson Reuters researchers.