The Data Annotation and Processing ToolTM is a part of MetaCoreTM, a pathway analysis software suite based on a manually-curated database from GeneGo, a Thomson Reuters business. It is designed to accelerate functional analysis of your Omics data.

Learn More About Data AnnotationThe Data Annotation & Processing Tool helps you quickly obtain the most significant and valuable components of scientific data, organize and statistically process the files, and use filters, workflows, or enrichments that are based on the standard vocabulary and ontology from MetaBase (the underlying database).

The wizard allows fast and easy data processing and annotation with metadata using controlled vocabulary. Intuitive tools help you to organize the data and analyze it in an easy to use workflows consisting of functional filters and ontology enrichment algorithms. Moreover, user metadata and analysis settings get captured and stored along with each sample’s properties upon the completion of the wizard. This provides a unique and standardized solution for anyone dealing with functional or pathway analysis of microarray data.

Use the Data Processing & Annotation Tool for:

  • Managing gene expression data and corresponding metadata
  • Annotation and organization of expression data files
  • Raw microarray data processing and statistical workup
  • Regulatory/Signaling Pathway Analysis of microarray data
  • Sample grouping and comparisons
  • Functional Analysis of Clinical Data

Enhance your MetaCore experience with the Data Annotation & Processing Tool, a unique add-on which allows you to:

  • Start with raw or processed data (Excel, .txt, .csv, .CEL format) or a .soft file from GEO
  • Breeze through annotation and file organization steps with our controlled vocabulary terms or add your own
  • Normalize and statistically process the data with RMA, FDR, filtering, DEG, and GSEA using GeneGo functional ontologies
  • Get your data with all the analysis settings and metadata factors saved in the Data Manager and stored within experiment properties
  • Launch a MetaCore analysis workflow immediately at the last step with a comprehensive report summary

PARSER

Auto-recognition and semi-automated processing of Excel, .txt, .csv, or .CEL format or .soft files from GEO

STATISTICAL FILTERS

  • Variable threshold filtering
  • Filter by selecting top 300 or top “n” genes from each data sample
  • FDR threshold filtering

FUNCTIONAL FILTERS

  • GO processes
  • Disease
  • Tissue
  • Sub cellular localization
  • Interaction types
  • Object types
  • Metabolites
  • Body fluids
  • Species/orthologs (human, mouse, rat, dog, chicken, worm, chimpanzee, bovine, zebrafish, fly, mosquito, mold, bread mold, baker's yeast, fission yeast, arabidopsis, rice, candida)

ONTOLOGIES THAT CAN BE USED FOR GSEA

  • Canonical Pathway Maps
  • GeneGo:
    • Process Networks
    • Metabolic Networks
    • Disease Networks
    • Drug Target Networks
    • Toxicity Networks
    • Diseases
  • GO:
    • Processes
    • Localization
    • Molecular Function

AUTOMATED WORKFLOWS WITH REPORTS

The last step of the wizard provides an option to launch a universal analysis workflow, which would provide functional analysis of the data with enrichments and ranking, as well as custom network building that captures the top interconnected modules for the dataset

Contact Us

North America

Tel: +1 800.336.4474
Tel: +1 215.386.0100
Fax: +1 215.386.2911

Europe, Middle East & Africa

Tel: +44 20.7433.4000

Latin America

Brazil: +55 11 8370 9845
Other Countries: +1 215 823 5674

Japan

Tel: +81 3.5218.6500
Tel: 0800 888.8855 (free dial from Japan only)
Fax: +81 3.5218.7840

Asia Pacific

Australia & New Zealand:
     +61 2 8587 7636
China: +86 10 5760 1200
India: +91 11 3044 6419
Korea: +82 2 2076 8100
South East Asia & Pakistan:
     +65 6775 5088
Taiwan: +886 2 2503 3034

Additional Information

GeneGo, a Thomson Reuters Business

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